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In Unity, the default methods that are part of the MonoBehaviour class, which all scripts derive from, are Start and Update.

The Start method is called before the first frame update, making it the ideal place to initialize variables or set up references. It only runs once during the lifetime of the script, ensuring that any setup code is executed at the beginning.

The Update method runs once per frame, making it suitable for regular checks and updates, such as monitoring input or applying physics. This continuous execution allows developers to create responsive and dynamic gameplay experiences by processing actions on each frame.

The other options include method names that do not correspond to Unity’s standard lifecycle methods. While methods such as Initialize and Run might be invoked by developers, they are not built-in Unity methods recognized by the framework. Similarly, Begin and Iterate do not align with Unity's predefined script lifecycle, which is specifically designed around the Start and Update methods.